According to the U.S. FOOD AND DRUG ADMINISTRATION (FDA): “More than 125,000 Americans die each year from adverse drug reactions, which are unwanted or dangerous effects caused by a drug”
The FDA has also stated: “Pharmacogenomics (DNA tests that test for how drugs effect individuals) can play an important role in identifying responders and non-responders to medications, avoiding adverse events, and optimizing drug dose”
With the advent of pharmacogenomic DNA testing it became increasingly clear that many patients take drugs that won’t work for them, leaving them at risk.
Pharmacogenomic DNA tests are scientifically proven and used by world renown centers of excellence like Cleveland Clinic and Mayo Clinic, but except for a relatively few specially trained physicians, most physicians do not consider the results of pharmacogenomic testing before prescribing a particular medication. Your physicians may not be fully aware of the newest information or even the dangers of taking medications with the potential of serious side effects for those who do not metabolize a drug properly. Like other specialists your doctor relies on, Parallel Certified Physicians can order these specialized tests, and explain the results to you and all your physicians, so everyone knows what’s safe for you.
A Harvard review of hospital charts indicated that “more than 2.7 million patients sustain serious ADRs annually.”
The Power of Precision Medicine — Real Life Examples
Precision Medicine is a new and better way to optimize treatment for patients based on their individual genetics, situation, and behaviors. Parallel MedCheck gives consumers and their doctors the ability to integrate precision medicine into their care and improve their outcome significantly.
Most physicians don’t realize that as many as half of their patients will not benefit from a prescribed medicine because of their individual genetics. Until now, neither you nor your physician had any way of knowing which drug would work best, and at what dose. Your genetics will determine if a drug will:
work at the normal dose
only work at a higher dose
only work at a lower dose
not work at any dose
put you at significant risk of severe harm or death
Turns out the old question people used to ask their doctor “If it was your wife or mother, what would you prescribe?” isn’t a good way to pick the best drug for you.
“90% of prescription drugs aren’t helping 30-50% of patients because of their genes”
Dr. Allen Roses Worldwide Vice-President of Genetics, GlaxoSmithKline, 2016
The more you know the better able you are to protect the ones you love
Child with ADHD
Treating ADHD is often a painstaking process of trial and error; trying each drug at various doses until improvement is attained. In the meantime the child’s struggle continues. A Parallel MedCheck™ can pinpoint the right med and the right dose in as little as 2 weeks.
“It’s such a relief to understand why my son’s medication wasn’t working. He kept telling me it wasn’t helping but I thought he was either not taking it or was wrong. To have the tension it was causing between us relieved is almost as wonderful as having him feel better! And I paid for it out of my HSA account. That was a nice surprise!”
Felita W, Ft. Lauderdale, Florida
Woman with heart disease
It is not uncommon for physicians to prescribe warfarin or other blood thinners to help prevent heart attacks and stroke. Unfortunately, although patients are closely monitored, these drugs are responsible for significant injury and even deaths. According to a major study done at the Mayo Clinic 23% of those on the drug had a genetic variant that affected the drug’s safety and effectiveness. By sharing the PGx test results with the prescribing physician, patients had a 31% reduction in hospitalization during the first 6 months alone.
“My mother had a horrible reaction to Warfarin. She ended up in a coma and barely survived. When my doctor recommended it to me I was too scared to take it. The Parallel MedCheck™ gave my doctor the information he needed to prescribe the right dose, and me the confidence to take it.”
Karen T, Baltimore Maryland
Man with prior bad reaction to a heart medication
Patients who experience an allergic or adverse reaction with one drug may be at higher risk for another problem. Protecting these patients is especially important. After a bad reaction to a drug following heart surgery put him in ICU for 2 weeks and almost killed him, the patient worried he might have another problem. To be certain he did a full sequence Parallel MedCheck™ test and discovered he had several genetic variants.
“46 drugs came up in my profile I should avoid entirely or use only with extra monitoring. So glad there was a good alternative available for almost all of them. I already switched 3 of the 5 drugs I’m on and have my list for the future.”
George C, San Clemente, California
People on multiple drugs
The average person over the age of 65 is on 14 drugs. Staggering, really. When a patient uses a drug that isn’t compatible with their genetics they often suffer more, and severe, side effects. It’s common for additional drugs to be prescribed to address those side effects. Being able to identify the right drug at the optimal dose can avoid many side effects as well as greatly improve the patient’s condition.
“My Mother was on 14 medications and seemed to be getting worse, not better. Based on your Parallel MedCheck™ report her doctors changed several of them and were able to eliminate 5 others that she was taking to control the side effects of the others.”
Cathy C, Minneapolis, Minnesota